Health risk assessment of heavy metals (lead and cadmium) in transgenic corn in Tehran

Authors

DOI:

https://doi.org/10.31763/bioenvipo.v2i2.584

Keywords:

Heavy metals, Transgenic corn, Lead, Cadmium, ICP

Abstract

Corn plant and the products made from corn   is one of the major transgenic concerning in the world, and due to public concerns about the presence of heavy metals in this product; the present study investigated the food safety in transgenic corn samples due to the presence of lead and cadmium. Iran has the highest exchange of agricultural products.  Five  packaged  popular brands of raw corn samples and one unpackaged one  as the bulk sample  were purchased from Tehran markets in 2021, and after confirming transgenicity by quantitative real-time PCR  and then wet digestion method.  The heavy metal contents in all studied samples were analyzed by inductively coupled plasma spectrometer. Bulk samples had the highest content of lead and cadmium compared to other packaged studied samples. The comparison of lead and cadmium compared to the maximum permissible levels set by the National and international standards revealed that the these toxic heavy metals ‘contents  in 100% of studied raw corn samples were  higher than the maximum limit.  The results of current study indicate that the Lead and Cadmium contents in the studied samples were 18 and 2.7 times higher than the maximum permissible limit (MPL).

Author Biographies

Soha Hatami, Islamic Azad University

Faculty of Pharmacy and Pharmaceutical Sciences, Tehran Medical Sciences

Zahra Mousavi, Islamic Azad University

Pharmacology-Toxicology Department, Faculty of Pharmacy and Pharmaceutical Sciences, Tehran Medical Sciences

Parisa Ziarati, Islamic Azad University

Department of Medicinal Chemistry, Tehran Medical Sciences

References

References

Nedjimi, B. Phytoremediation: A sustainable environmental technology for heavy metals decontamination. SN Applied Sciences 3, 1-19 (2021). https://doi.org:10.1007/s42452-021-04301-4

Ozyigit, I. I., Can, H. & Dogan, I. Phytoremediation using genetically engineered plants to remove metals: a review. Environmental Chemistry Letters 19, 669-698 (2020). https://doi.org:10.1007/s10311-020-01095-6

Das, S., Das, S. & Ghangrekar, M. M. Efficacious bioremediation of heavy metals and radionuclides from wastewater employing aquatic macro- and microphytes. J Basic Microbiol 62, 260-278 (2022). https://doi.org:10.1002/jobm.202100372

Gavrilescu, M. Enhancing phytoremediation of soils polluted with heavy metals. Curr Opin Biotechnol 74, 21-31 (2022). https://doi.org:10.1016/j.copbio.2021.10.024

Sarad, N., Rathore, M., Singh, N. K. & Kumar, N. in 4th International Crop Science Congress (ed T. et al. Fisher) (The Regional Institute, Brisbane, 2004).

International Service for the Acquisition of Agri-biotech Applications. (International Service for the Acquisition of Agri-biotech Applications, 2016).

Report of Iran Chamber of Commerce. A look at the statistics of import, clearance and distribution of livestock inputs, <https://www.tzccim.ir/News/1613/> (2019).

Abdi, L. et al. Potentially toxic elements (PTEs) in corn (Zea mays) and soybean (Glycine max) samples collected from Tehran, Iran: a health risk assessment study. International Journal of Environmental Analytical Chemistry 102, 4640-4651 (2020). https://doi.org:10.1080/03067319.2020.1786548

Iran's cereal production to rise 34% in 2022: FAO, <https://www.tehrantimes.com/news/473542/Iran-s-cereal-production-to-rise-34-in-2022-FAO#:~:text=Iran's%20corn%20imports%20are%20seen,which%20was%203.086%20million%20tons.> (2022).

Gheshlagh, F. S.-N., Ziarati, P. & Bidgoli, S. A. Seasonal fluctuation of heavy metal and nitrate pollution in ground water of farmlands in Talesh, Giran, Iran. International Journal of Farming and Allied Sciences 2, 836-841 (2013).

Hosseinabady, B. T., Ziarati, P., Ballali, E. & Umachandran, K. Detoxification of heavy metals from leafy edible vegetables by agricultural waste: Apricot pit shell. Journal of Environmental & Analytical Toxicology 08 (2018). https://doi.org:10.4172/2161-0525.1000548

Skrbic, B. D., Buljovcic, M. & Antic, I. Comprehensive assessment of heavy elements and evaluation of potential human health risk in the urban environment: a case study from Novi Sad, Serbia. Environ Sci Pollut Res Int 29, 38551-38566 (2022). https://doi.org:10.1007/s11356-022-18733-x

Shams, M. et al. Heavy metals exposure, carcinogenic and non-carcinogenic human health risks assessment of groundwater around mines in Joghatai, Iran. International Journal of Environmental Analytical Chemistry 102, 1884-1899 (2020). https://doi.org:10.1080/03067319.2020.1743835

Zhai, Y., Zheng, F., Li, D., Cao, X. & Teng, Y. Distribution, genesis, and human health risks of groundwater heavy metals impacted by the typical setting of songnen plain of NE China. Int J Environ Res Public Health 19 (2022). https://doi.org:10.3390/ijerph19063571

Ziarati, P., Farasati Far, B., Mashayekhi, E. & Sawicka, B. Removing arsenic by food-processing waste (Zizyphus jujuba seeds) and study on its adsorptive properties. Scientific and technical journal (Technogenic and Ecological Safety) 5, 62-70 (2019). https://doi.org:10.5281/zenodo.2604648

Ziarati, P., Mohsenin Moshiri, I. & Sadeghi, P. Bio-adsorption of heavy metals from aqueous solutions by natural and modified non-living roots of wild Scorzonera incisa DC. Journal of Scientific Discovery 1 (2017). https://doi.org:10.24262/jsd.1.1.17010

Ziarati, P., Vambol, V. & Vambol, S. Use of inductively coupled plasma optical emission spectrometry detection in determination of arsenic bioaccumulation in Trifolium pratense L. from contaminated soil. Ecological Questions 31 (2019). https://doi.org:10.12775/eq.2020.003

Kushwaha, A., Hans, N., Kumar, S. & Rani, R. A critical review on speciation, mobilization and toxicity of lead in soil-microbe-plant system and bioremediation strategies. Ecotoxicol Environ Saf 147, 1035-1045 (2018). https://doi.org:10.1016/j.ecoenv.2017.09.049

Saeedifar, F., Ziarati, P. & Ramezan, Y. Nitrate and heavy metal contents in eggplant (Solanum melongena) cultivated in the farmlands in the south of Tehran-Iran. International Journal of Farming and Allied Sciences 3, 60-65 (2014).

Luo, Y. et al. Quantitative tracing of uptake and transport of submicrometre plastics in crop plants using lanthanide chelates as a dual-functional tracer. Nat Nanotechnol 17, 424-431 (2022). https://doi.org:10.1038/s41565-021-01063-3

Kumar, A. et al. Lead toxicity: Health hazards, influence on food chain, and sustainable remediation approaches. Int J Environ Res Public Health 17 (2020). https://doi.org:10.3390/ijerph17072179

Flora, G., Gupta, D. & Tiwari, A. Toxicity of lead: A review with recent updates. Interdiscip Toxicol 5, 47-58 (2012). https://doi.org:10.2478/v10102-012-0009-2

Kasten-Jolly, J. & Lawrence, D. A. Sex-specific effects of developmental lead exposure on the immune-neuroendocrine network. Toxicol Appl Pharmacol 334, 142-157 (2017). https://doi.org:10.1016/j.taap.2017.09.009

Du, B. et al. Environmental and human health risks from cadmium exposure near an active lead-zinc mine and a copper smelter, China. Sci Total Environ 720, 137585 (2020). https://doi.org:10.1016/j.scitotenv.2020.137585

Natasha, Shahid, M., Khalid, S. & Saleem, M. Unrevealing arsenic and lead toxicity and antioxidant response in spinach: a human health perspective. Environ Geochem Health 44, 487-496 (2022). https://doi.org:10.1007/s10653-021-00818-0

Fatahi, A., Ziarati, P., Jafarpour, A. & Cruz-Rodriguez, L. Heavy metal removal from edible leafy vegetable by low cost novel adsorbents: A short review. Journal of Scientific Discovery 4 (2020).

Liu, Y. et al. Potential health risk in areas with high naturally-occurring cadmium background in southwestern China. Ecotoxicol Environ Saf 112, 122-131 (2015). https://doi.org:10.1016/j.ecoenv.2014.10.022

Alloway, B. J. Heavy metals in soils. (1995).

Yazdanparats, S., Ziarati, P. & Asgarpanah, J. Nutritive values of some Iranian Manna. Biosciences Biotechnology Research Asia 11, 1025-1029 (2014). https://doi.org:10.13005/bbra/1378

Kabata-Pendias, A. Trace elements in soils and plants. (2010).

Quezada-Hinojosa, R., Föllmi, K. B., Gillet, F. & Matera, V. Cadmium accumulation in six common plant species associated with soils containing high geogenic cadmium concentrations at Le Gurnigel, Swiss Jura Mountains. Catena 124, 85-96 (2015). https://doi.org:10.1016/j.catena.2014.09.007

Yang, Y., Nan, Z. & Zhao, Z. Bioaccumulation and translocation of cadmium in wheat (Triticum aestivum L.) and maize (Zea mays L.) from the polluted oasis soil of Northwestern China. Chemical Speciation & Bioavailability 26, 43-51 (2015). https://doi.org:10.3184/095422914x13888342841789

Fahad, S. et al. Grain cadmium and zinc concentrations in maize influenced by genotypic variations and zinc fertilization. CLEAN - Soil, Air, Water 43, 1433-1440 (2015). https://doi.org:10.1002/clen.201400376

Taghipour, H. & Mosaferi, M. Heavy metals in the vegetables collected from production sites. Health Promot Perspect 3, 185-193 (2013). https://doi.org:10.5681/hpp.2013.022

Zhang, H., Yan, J., Niu, J., Wang, H. & Li, X. Association between lead and cadmium co-exposure and systemic immune inflammation in residents living near a mining and smelting area in NW China. Chemosphere 287, 132190 (2022). https://doi.org:10.1016/j.chemosphere.2021.132190

Mostafidi, M. et al. Bioaccumulation of the heavy metals contents in green leafy vegetables. Journal of Nutrition Food Science and Technology 2, 1-7 (2021).

Mokhtarzadeh, M., Ziarati, P. & Hosseini, J. Novel method in removing nickel and cobalt from pharmaceutical laboratories' effluent by green Bio-Adsorbent: Tomato pomace. Advances in Biology & Earth Sciences 6, 221-234 (2021).

Ziarati, P. et al. The contaminated water pre-treatment method. Ukraine patent No u 144368 (2020).

Tajik, S., Ziarati, P. & Cruz-Rodriguez, L. Coffee waste as novel Bio-adsorbent: Detoxification of Nickel from contaminated spil and coriandrum sativum. Journal of Bioscience & Biomedical Engineering 1 (2020).

Shokri, F., Ziarati, P. & Mousavi, Z. Removal of selected heavy metals from pharmaceutical effluent by Aloe Vera L. Biomedical and Pharmacology Journal 9, 705-713 (2016). https://doi.org:10.13005/bpj/993

Pourzare, A., Ziarati, P., Mousavi, Z. & Faraji, A. R. Removing cadmium and nickel contents in basil cultivated in pharmaceutical effluent by chamomile (Matricaria chamomilla L.) Tea Residue. Journal of Scientific Discovery 1 (2017). https://doi.org:10.24262/jsd.1.1.17006

Ziarati, P. & Tosifi, S. Comparing some physical and chemical properties of green olive (Olea europea L.) in Iran association with ecological conditions. International Journal of Plant, Animal and Environmental Science 4, 519-528 (2014).

Institute of Standards and Industrial Research of Iran. Vol. National standard NO. 12968 (Institute of Standards and Industrial Research of Iran, 2010).

Anjum, S. A. et al. Cadmium toxicity in Maize (Zea mays L.): consequences on antioxidative systems, reactive oxygen species and cadmium accumulation. Environ Sci Pollut Res Int 22, 17022-17030 (2015). https://doi.org:10.1007/s11356-015-4882-z

Choi, S. H. et al. Heavy metal determination by Inductively Coupled Plasma – Mass Spectrometry (ICP-MS) and Direct Mercury Analysis (DMA) and arsenic mapping by Femtosecond (fs) – Laser Ablation (LA) ICP-MS in Cereals. Analytical Letters 52, 496-510 (2018). https://doi.org:10.1080/00032719.2018.1471484

Vaghar, S. A. & Solgi, E. Investigation of the effect of irrigation with wastewater on accumulation of cadmum and lead in the soil and cultivated vegetables (Case study: Hamedan city). Journal of Environmental Science and Technology 21, 139-150 (2019).

Bamagoos, A. A., Alharby, H. F. & Abbas, G. Differential uptake and translocation of Cadmium and Lead by Quinoa: A multivariate comparison of physiological and oxidative stress responses. Toxics 10 (2022). https://doi.org:10.3390/toxics10020068

Iftikhar, A. et al. Salinity modulates lead (Pb) tolerance and phytoremediation potential of quinoa: a multivariate comparison of physiological and biochemical attributes. Environ Geochem Health 44, 257-272 (2022). https://doi.org:10.1007/s10653-021-00937-8

Amjad, M. et al. Assessment of cadmium and lead tolerance potential of quinoa (Chenopodium quinoa Willd) and its implications for phytoremediation and human health. Environ Geochem Health 44, 1487-1500 (2022). https://doi.org:10.1007/s10653-021-00826-0

Rahdarian, S. et al. Heavy metal phytoremediation potential of Vigna radiata (L.) Wilczek for use in contaminated regions of West Karun River, Iran. Journal of Agriculture and Food Research 10 (2022). https://doi.org:10.1016/j.jafr.2022.100373

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Published

2022-12-30

How to Cite

1.
Hatami S, Mousavi Z, Ziarati P. Health risk assessment of heavy metals (lead and cadmium) in transgenic corn in Tehran. Biological. environ. pollut. [Internet]. 2022Dec.30 [cited 2024Apr.26];2(2):49-5. Available from: http://pubs.ascee.org/index.php/bioenvipo/article/view/584

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